Seven coaches of Shaktipunj Express derail in Uttar Pradesh

first_imgSeven coaches of the Jabalpur-bound Shaktipunj Express derailed on Thursday in Sonbhadra district of Uttar Pradesh, a railway official said.“The accident occurred at around 6:25 am  and we have already cleared out the site,” railway ministry spokesperson Anil Saxena said.“All passengers were put on the remaining coaches and by 7:28 AM all of them had left the spot. All of them are safe and no one was injured in the accident,” he said.The train was running at a speed of about 40 km/hr which, officials say, prevented any injuries when the incident occurred.This is the third such derailment in the State in less than a month.On August 19, the Utkal Express had derailed in Muzaffarnagar district, killing 22 people and injuring 156.About 100 passengers were wounded when 10 coaches of Kaifiyat Express train derailed after crashing into a dumper which strayed on to the tracks in Auraiya district on August 23.last_img read more

Rape case filed against Congress MLA

first_imgA case was registered on the court’s order against Congress MLA Johari Lal Meena, representing Rajgarh-Laxmangarh constituency of Rajasthan’s Alwar district, on charges of raping a 38-year-old widow several times during the last two years and threatening to release the video of the alleged act. The FIR was registered at Raini police station over the weekend.The woman, who filed a complaint in the Judicial Magistrate’s court for registration of FIR, alleged that Mr. Meena, 68, whom she had met two years ago, took her to a hotel in the temple town of Mehandipur Balaji on the pretext of taking her to a doctor when she was ill. At the hotel, the MLA allegedly gave her some medicines and raped her when she fell unconscious, according to the complaint.Mr. Meena denied the charge on Saturday and said the complaint against him was a “political conspiracy” hatched to prevent him from campaigning for his party in the Lok Sabha election. “The objective is to damage the prospects of Congress. This is also a ploy to reduce my popularity in the public,” said Mr. Meena, who had defeated his BJP rival with a margin of 30,298 votes in the 2018 Assembly election.The complainant alleged that Mr. Meena had made a video of the act and started blackmailing her with the threat to release it. She also alleged that the MLA had forced her to establish a physical relationship with him several times.The FIR was registered under Sections 376 (rape), 384 (extortion) and 328 (causing hurt by means of poison) of Indian Penal Code and investigation handed over to CB-CID in view of the accused being a legislator.last_img read more

IPL 2019: Virat Kohli’s latest photo on social media goes viral. Have you seen it yet?

first_imgVirat Kohli is going through one of his worst seasons in the Indian Premier League. Royal Challengers Bangalore have lost 7 out of their 8 matches in the 2019 IPL and are languishing at the bottom of points table.Virat Kohli, who scored 973 runs and hit 4 hundreds in 2016, has managed only 278 runs so far this year. Yet. Kohli is far from dejected and continues to believe his team can bounce back and have a say in the 2019 IPL.Royal Challengers Bangalore have lost matches against Chennai Super Kings, Mumbai Indians (twice), Sunrisers Hyderabad, Rajasthan Royals, Kolkata Knight Riders and Delhi Capitals. Their solitary win has come against Kings XI Punjab who are currently No.4 in the points table.On Tuesday, Virat Kohli hosted a dinner for his RCB teammates. A day later, Virat Kohli posted a photo and it went viral within minutes. On Tuesday, Virat Kohli hosted a dinner for his RCB teammates. (Image: Instagram/devpadikkal19) On Tuesday, Virat Kohli hosted a dinner for his RCB teammates.(Image: Instagram/yuzi_chahal23) On Tuesday, Virat Kohli hosted a dinner for his RCB teammates.(Image: Instagram/himmatsingh89)Sat Shri Akal saarreyaan nu! pic.twitter.com/KWMACuCzuQVirat Kohli (@imVkohli) April 17, 2019Royal Challengers Bangalore are now in Kolkata where they take on the Kolkata Knight Riders at the Eden Gardens on April 19 before heading home to face table-toppers Chennai Super Kings on April 21.Virat Kohli will need to lead from the front against two of the most well-balanced teams in the IPL with help from the dangerous AB de Villiers.advertisementOn Monday (April 15), Virat Kohli met the national selectors to pick India’s squad for the 2019 Cricket World Cup. In England, Kohli will be under pressure as captain and batsman as India look to win their 3rd World Cup.Also Read | Virat Kohli has been scoring runs, will be a threat in World Cup: Lockie FergusonAlso Read | IPL 2019: Anushka Sharma keeps me positive, says Virat Kohli after RCB’s 1st winlast_img read more

ESPN Mistakes Devin Booker For Arrested Notre Dame DB Devin Butler

first_imgESPN accidentally uses Devin Booker photo on Notre Dame report.ESPN.ESPN’s SportsCenter made quite an error in their broadcast of Notre Dame cornerback Devin Butler’s arrest last night.First, Butler was arrested yesterday on preliminary felony charges of battery to law enforcement and resisting arrest. Then, when reporting the arrest on Saturday night’s SportsCenter, ESPN managed to confuse Butler with Phoenix Suns guard Devin Booker. They very clearly selected the wrong photo for the broadcast.The hiccup definitely didn’t go unnoticed by viewers. Social media lit up, calling out the station for the error..@SportsCenter whoops. @DevinBook pic.twitter.com/sHKYdf1ybT— JTrain (@purplePHXorange) August 21, 2016When they realized the mistake, SportsCenter issued an apology. Anchor Zuban Memento read the statement after the commercial break.You can watch it below:@DevinBook @espn @SportsCenter pic.twitter.com/uAJAgVOWF4— JTrain (@purplePHXorange) August 21, 2016The transcription of his apology is below:“We are back on SportsCenter, and an apology we’d like to make. When reporting on a story earlier this hour on Notre Dame cornerback Devin Butler, we accidentally used a photo of the Phoenix Suns’ Devin Booker. We all here at SportsCenter do sincerely apologize for that mistake.”Butler has since been indefinitely suspended by Notre Dame’s football program.last_img read more

Trudeau visits peacekeepers in Mali defends decision not to extend mission

first_imgGAO, Mali — Prime Minister Justin Trudeau is returning from Mali this evening after paying a surprise visit to Canadian peacekeepers at their hot and dusty UN base there only days before Christmas.The trip was Trudeau’s first — and likely only — visit to the West African nation, where about 250 Canadian peacekeepers have been providing lifesaving medical evacuations and transporting equipment and personnel.After watching a mock evacuation and serving the peacekeepers a pre-Christmas dinner, Trudeau told the troops they were continuing the Canadian military’s long tradition of helping around the world.Yet even as he emphasized the importance of bringing peace to Mali, the prime minister defended his government’s refusal to extend Canada’s mission by several months next summer.Romanian peacekeepers will take over in Mali next year, but they aren’t expected to arrive until several months after the Canadians have stopped operations.Sources say the United Nations wants Canada to extend its mission to prevent a gap.Trudeau, whose government also has yet to deploy a promised transport aircraft to Uganda and a 200-strong rapid reaction force for the UN, played down the effects of a gap and said Canada and the UN are working to ensure a smooth transition.The Canadian Presslast_img read more

Nokia in advanced talks to buy its rival AlcatelLucent

first_imgAdvertisement Telecommunications-equipment maker Nokia Corp. has revealed that it is in advanced talks to buy French rival Alcatel-Lucent.If a deal is reached, it will create a new global networking behemoth to rival Sweden’s Ericsson and China’s Huawei Technologies.The deal is currently under consideration and would entail Nokia making a public offer for Alcatel-Lucent stock, the companies said. – Advertisement – Alcatel-Lucent’s market capitalization stands at roughly EUR11 billion, while Nokia’s market capitalization is about EUR28 billion.The news made Alcatel-Lucent’s shares to jump up 13% to EUR4.38 in morning trading in Paris.A Nokia-Alcatel merger deal would reshape the telecommunications-equipment business by creating a company with a combined 2014 revenue of EUR25.9 billion.Via Market Watchlast_img read more

Got Your PostDeath Checklist Grace Can Help

first_img Register Now » 5 min read Learn how to successfully navigate family business dynamics and build businesses that excel. Free Webinar | July 31: Secrets to Running a Successful Family Business Sophia Stuart Startups Got Your Post-Death Checklist? Grace Can Help. Next Article February 17, 2017center_img Grace connects people to end-of-life information and services online. Until fairly recently, death and dying were subjects usually hidden from view. But the digital age has opened up new possibilities for end-of-life organization, from figuring out advance directives, hospice decisions and funeral arrangements to contacting financial institutions and gathering documentation.One such possibility is a tech startup called Grace, which connects people to end-of-life information and services online. It’s the brainchild of Alex Kruger and Annie Luchsinger, and is currently in testing mode at Cedars Sinai in Los Angeles.The business model now requires providers to pay to be listed after a screening process conducted by the Grace team. Kruger and Luchsinger want to keep Grace free to families and build on their directory of providers with a suite of online tools to help patients and families navigate what needs to be done, from one central resource.”The more we talk to families, the better our product can become,” said Kruger. “Grace is the intersection of solutions, a triage system if you like, from connecting with quality hospice or senior care providers, to an after-death checklist. Our goal is to be the catalyst for solutions no matter what point you are at when making difficult life-stage decisions.”Right now, the majority of traffic comes from desktops, as families gather around to use Grace as a starting point for tough conversations. The future might get more mobile as individuals take control of their own plans ahead of time.Grace got its start on the East Coast under a different name, Attendant.”Two things happened around the same time: I was working in another business and a friend mentioned the problems inherent in the end-of-life space. Then my great-uncle died,” Kruger told PCMag. “I didn’t have a good understanding of what it takes to sort out everything from closing out accounts, talking to providers, getting affidavits of domicile, and so on. I asked my family how I could help, and the idea for a digital solution began to emerge.”Kruger had been looking for a new business idea. After stints at a Shanghai biopharma company and IBM, he moved to the startup world and worked for Belly, Fooda and SpotHero. But he wanted to branch out and started Attendant to explore the end-of-life space.Not long after, Luchsinger joined him as Attendant’s first hire from HitchSwitch, a newlywed name-changing company; she’d also previously worked as a buyer for Rue La La.The duo decided to reolocate from the East Coast to Los Angeles. “We wanted to be somewhere that has a digitally forward population, where people are open to using a service like Grace, that’s online. California made the most sense to us,” Kruger said.They applied to the Techstars program, which mentors promising startups, and were accepted into the Boulder, Colorado, program. There, they rebuilt the idea as Grace in partnership with Cedars Sinai.”It was through [Techstars] that Cedars Sinai found out about us,” Luchsinger told PCMag. “They were looking for a digital-first company, with a new mindset and method, to help their patients and their families navigate end-of-life tasks.”They thought Grace might be a really interesting fit; we applied and got in, joining the Techstars Healthcare Accelerator 2016. We emerged with an innovative pilot that allows any patient or family member experiencing an end-of-life event at Cedars-Sinai to call us for guidance and assistance.””The pilot has been live since July 2016,” added Kruger. “Available initially as a resource through their Inpatient Specialty Program, but it expanded rapidly. Grace made awesome waves throughout the hospital and we now get referred by staff in the Emergency Department, ICU and beyond. The goal is to jump in, to have those tough conversations and provide clarity about who to trust in the end-of-life space.”What’s next for Grace? Luchsinger said they hope to be in four additional geographic areas by July 2017 with new content above and beyond the directory. “We’re also starting to aggregate and acquire reviews of providers, and will be building that in next year,” she confirmed.Having been through several surgeries myself, including one life-threatening one, I could not have been admitted to a hospital without providing an Advance Directive, my end-of-life instructions. It was a deeply odd situation sitting in my attorney’s office, setting out under what circumstances I’d let doctors unplug me from life support, and it got me thinking about how you sort out all the administration required post-death. Using a service like Grace from the comfort of my own home would have given me peace of mind. It’s a welcome solution to wrapping everything up neatly before one does have to depart. Add to Queue Image credit: Grace via PC Mag This story originally appeared on PCMag –shares Digital Strategist and Technology Columnistlast_img read more

Should Uber and Lyft Get in the Carpool Lane Together Start Up

first_img Opinions expressed by Entrepreneur contributors are their own. Should Uber and Lyft Get in the Carpool Lane Together? — Start Up Your Day Roundup March 16, 2016 –shares Start Up Your Day Looking for the latest headlines in small business, innovation and tech? Our Start Up Your Day recaps are posted every morning to keep you current.A change of heart. Less than 24 hours after Microsoft booted a cloud sharing company as a sponsor from its upcoming tech conference, the company changed its mind and reinvited the startup. Business Insider has more.What would you do with $2 billion? If your startup needs a few ideas, Accel’s got a couple suggestions.Friends, not rivals? Lyft and Uber have been long been fierce competitors but a new study suggests business would be better if the two ride sharing companies became allies.If you see something, say something. In Japan, Airbnb has unveiled a way for neighbors to complain to the service if hosts’ guests get too rowdy, reports The Verge. The feature should launch in the U.S. next month.Switching things up. The average Instagram user misses out on about 70 percent of the content in their news feed. To remedy the problem, the photo-sharing application announced plans to change the order of posts in the feed based on your level of interest, according to TechCrunch.The last word (for now). Apple filed its final response before it faces off against the FBI in federal court over issues of privacy and encryption. Business Insider has the entire brief.Do as I say. Looking for a good read? Warren Buffett made a list of 18 books he thinks everyone should check out. Register Now » Staff writer. Frequently covers franchise news and food trends. Free Webinar | July 31: Secrets to Running a Successful Family Business Add to Queue Lindsay Friedman Image credit: Uber | Lyft Next Article Learn how to successfully navigate family business dynamics and build businesses that excel. 2 min readlast_img read more

Facebook Hit With Lawsuit Over Plan to Issue New Stock

first_img May 2, 2016 –shares This story originally appeared on Reuters Image credit: endermasali | Shutterstock.com | Enhanced by Entrepreneur Add to Queue Facebook Facebook Hit With Lawsuit Over Plan to Issue New Stock Reuters center_img Attend this free webinar and learn how you can maximize efficiency while getting the most critical things done right. 2 min read A Facebook Inc. shareholder filed a proposed class action lawsuit on Friday in a bid to stop the company’s plan to issue new Class C stock, calling the move an unfair deal to entrench Chief Executive Mark Zuckerberg as controlling shareholder.The lawsuit, filed in the Delaware Court of Chancery, followed the social networking company’s announcement on Wednesday of its plan to issue the shares.The rejiggering of Facebook’s share structure is effectively a three-for-one stock split. Zuckerberg’s said in December that he intends to put 99 percent of his Facebook shares into a new philanthropy project focusing on human potential and equality.The lawsuit contends that a Facebook board committee which approved the share deal “did not bargain hard” with Zuckerberg “to obtain anything of meaningful value” in exchange for granting Zuckerberg added control.In a statement, Facebook said the plan “is in the best interests of the company and all stockholders.” The company has said keeping Zuckerberg at the helm is key to its future success.Facebook plans to create a new class of shares that are publicly listed but do not have voting rights. Facebook will issue two of the so-called “Class C” shares for each outstanding Class A and Class B share held by shareholders. Those new Class C shares will be publicly traded under a new symbol.Zuckerberg “wishes to retain this power, while selling off large amounts of his stockholdings, and reaping billions of dollars in proceeds,” the lawsuit said.”The issuance of the Class C stock will, in effect, have the same effect as a grant to Zuckerberg of billions of dollars in equity, for which he will pay nothing,” it said.Google settled a lawsuit in 2013 shortly before trial which cleared the way for that company to execute a similar plan.(Reporting by Dan Levine; Editing by Bernard Orr and Tom Brown) Free Webinar | Sept 5: Tips and Tools for Making Progress Toward Important Goals Next Article Register Now »last_img read more

PMG Launches Marketing Intelligence Platform — Meet Alli

first_imgAlli, PMG’s Marketing Intelligence Platform, Combines the Power of Humans and Technology to Give Marketers a Single View of Their Data in Order to Provide More Personalized Experiences to Their CustomersPMG, a global, independent digital company introduced Alli, the company’s proprietary marketing intelligence platform that unifies advertisers’ data from disparate systems, providing immediate business insights and actions at scale.PMG introduces Alli, the company’s proprietary marketing intelligence platform that unifies advertisers’ data from disparate systems, providing immediate business insights and actions at scale.As the digital industry becomes increasingly complex, and data ownership and privacy practices face more regulatory scrutiny, consumers’ demand for better, more relevant advertising and content experiences has only grown stronger. Today’s marketers are now tasked with externally delivering personalized messaging while improving performance and upholding privacy compliance. With advertisers also facing walled gardens and losing access to third-party data, technology that drives enhanced performance and a level of human connection has not been possible until Alli.Marketing Technology News: Facebook Shoots Down ‘Innovation’ Chaos with a New CryptoCurrency Platform ‘Calibra’“Alli helps brands reimagine their marketing investments, enabling marketers to easily create more effective campaigns and truly improve overall customer lifetime value,” said George Popstefanov, CEO, PMG. “Brand marketers are increasingly expected to deliver in the face of changing data practices and an abundance of data points. With Alli, we’re giving brands a single view of their data so together, we can consistently build campaigns on a very personalized, human level.”PMG’s Alli was built with consideration for the fact that to understand customer behavior, marketers must connect the millions of untethered data points across different platforms, and connect publisher data to internal CRM and business performance data in order to gain better insights and provide a clear path to action.Marketing Technology News: Profisee Adds Market Analyst Bill O’Kane to Leadership TeamAlli enables brands to granularly segment key data sets to answer and provide actionable recommendations to business-critical questions across specific audience cohorts, demographics and characteristics. This capability ensures they can create insights-driven, personalized and effective campaigns that better engage customers on an individual level. By identifying their customers’ tendencies and measuring behavior in real-time, brands can take swift action to optimize entire campaigns – answering questions such as “which advertising channels are performing better than others?” and “what is my best-performing creative content?”With Alli, brands gain a competitive advantage through the following key data activities: data aggregation, cleansing and normalization, automation, and activation. No matter how many internal and external data sources a brand has, Alli consolidates data to help better inform decision-making. And in doing so, Alli gives brands full ownership of their data, eliminates data silos and allows marketers to evaluate campaigns on a more granular level so they can increase audience reach, engagement and conversion. On average, PMG customers have connected over 30 different sources of data, including internal business data and external publishers’ performance information.The main components and integrated services as part of Alli include:Data Management — creates a common language for all of the brand’s data, with consistency, accuracy and security.Insights and Visualization — allows the brand to distill the right information and answer the hardest questions, providing new levels of understanding, quality and trust in decision-making.Actions and Automation — gives brands the power to unlock new ways of connecting with audiences at scale through speed to market, efficiency and peace of mind.In addition to these core services, Alli was built to also tackle unique, complex business challenges through custom-built solutions. By utilizing the underlying components of the platform, PMG’s Alli can be tailored to meet any brands’ needs with flexibility and scale.Alli has been several years in the making by combining PMG’s four core technology products into one integrated and cohesive platform. Alli unlocks access and visibility into brands’ own data, allowing PMG services to activate marketing campaigns at scale globally. Alli is already in action across 100% of PMG’s clients. When it comes to creating digital marketing campaigns with publishers like Google, over 50% of PMG’s media investment is being driven by first- and third-party audience data which has consistently driven better performance.Marketing Technology News: PX Launches Private Marketplaces to Support Direct Advertiser to Publisher Engagement“The consumer journey is more complex than ever before, and people expect more from your ads as a result,” said Vicky Homan, Global Product Lead, Google. “Tools that can combine your data across disparate sources hold the key to making ads relevant, immediate and useful for your customers in light of these heightened expectations.” PMG Launches Marketing Intelligence Platform — Meet Alli Business WireJune 21, 2019, 11:04 pmJune 21, 2019 crmData ManagementMarketing TechnologyNewspersonalizationPMG’s Alli Previous ArticleHaoqipei Secures US $60 Million in Series D Funding to Further Accelerate Growth of its Online B2B Auto Parts MarketplaceNext ArticleYext Study: 58% Of Healthcare and Pharmaceutical Marketers Say Their Marketing Management Strategy Needs Major Improvementslast_img read more

NIH starts clinical trial of drug to treat cravings associated with opioid

first_img Source:https://www.niaid.nih.gov/news-events/nih-test-experimental-drug-curb-opioid-cravings Reviewed by James Ives, M.Psych. (Editor)Mar 22 2019A clinical trial of an experimental drug designed to treat cravings associated with opioid use disorder (OUD) has begun in the National Institutes of Health Clinical Center. The Phase I trial in healthy adults will assess the safety of the experimental compound, ANS-6637, and how it is processed in the body when given with another drug that is processed by the same liver enzyme pathway. The NIH’s National Institute of Allergy and Infectious Diseases (NIAID) is helping to conduct the trial, which is funded through NIH’s Helping to End Addiction Long-Term (HEAL) Initiative, a comprehensive program to accelerate research efforts to stem the public health crisis of OUD.”Opioid drugs play an important role in controlling pain, but have strong potential for misuse, as evidenced by the opioid epidemic gripping every region of the United States. Opioid misuse and addiction are associated with high-risk behaviors that may lead directly or indirectly to infections with HIV or hepatitis C virus, to other illnesses, and to premature death,” said NIAID Director Anthony S. Fauci, M.D. “Because substance use disorders and certain infectious diseases are often intertwined, infectious disease physicians must understand and be prepared to address both issues in order to provide optimal care for their patients.”Opioid use causes a surge of the neurotransmitter dopamine in the brain, and habitual use ‘rewires’ the brain’s reward system, possibly generating irresistible cravings to both opioids and associated cues, like injecting equipment or drug use partners.”At this time, there are few pharmacological interventions that specifically target the cravings felt by some patients who have physical dependence or opioid use disorder,” noted Henry Masur, M.D., chief of the Clinical Center’s Critical Care Medicine Department, and a principal investigator in the new trial. “This trial will lay the groundwork for future studies; together these may lead to effective treatments for the drug cravings that impede the pursuit of sobriety.”Related StoriesResearch team to create new technology for tackling concussionHIV DNA persists in spinal fluid despite treatment, linked to cognitive impairmentNovel vaccine against bee sting allergy successfully testedANS-6637 is being developed by Amygdala Neurosciences, Inc. Pre-clinical studies in animals suggest that the compound inhibits the dopamine surge that accompanies opioid use in persons with OUD, without impacting the background levels of dopamine required for normal brain functions.The trial will enroll up to 50 healthy adults aged 18 through 65 years. Participants will stay in the Clinical Center in Bethesda, Maryland, for 10 days and return for a final outpatient visit after one week. On the first day, volunteers will receive a single dose of the licensed drug midazolam. Midazolam was chosen because its processing by the body is well understood, acting as a template for liver metabolism. They will receive no drug on day two. On study days three through seven, volunteers will receive 600 milligrams of ANS-6637 each day. On day eight, participants will receive midazolam and ANS-6637 together to see how the investigational agent affects midazolam levels. This in turn will help researchers understand how ANS-6637 is processed by the body, setting up the next phase of scientific investigation in patients with OUD.”Opioid use disorder is a treatable medical illness that, much like in the early days of HIV, has been held back from scientific advancement by stigma and misconception,” said Sarah Kattakuzhy, M.D., associate investigator and assistant professor at the Institute of Human Virology at the University of Maryland School of Medicine in Baltimore. “With the support of the HEAL Initiative and NIAID, we can now assess a novel potential therapeutic in the treatment of OUD. If proven effective, ANS-6637 could be part of a comprehensive package of services, including harm reduction, opioid agonist therapy and behavioral interventions, enabling us to offer our patients the highest level of evidence-based therapy.” Dr. Kattakuzhy and colleagues are planning further study of ANS-6637 as a treatment for OUD in clinical trials at the University of Maryland School of Medicine.last_img read more

3Dprinted artificial tissues could help heal people with sports injuries

first_imgReviewed by James Ives, M.Psych. (Editor)Mar 29 2019Bioscientists are moving closer to 3D-printed artificial tissues to help heal bone and cartilage typically damaged in sports-related injuries to knees, ankles and elbows.Scientists at Rice University and the University of Maryland reported their first success at engineering scaffolds that replicate the physical characteristics of osteochondral tissue – basically, hard bone beneath a compressible layer of cartilage that appears as the smooth surface on the ends of long bones.Injuries to these bones, from small cracks to pieces that break off, can be painful and often stop athletes’ careers in their tracks. Osteochondral injuries can also lead to disabling arthritis.Related StoriesEngineered stem cells offer new treatment for metastatic bone cancerPersonalizing Nutritional Medicine With the Power of NMRDon’t Miss the Blood-Brain Barrier Drug Delivery (B3DD) Summit this AugustThe gradient nature of cartilage-into-bone and its porosity have made it difficult to reproduce in the lab, but Rice scientists led by bioengineer Antonios Mikos and graduate student Sean Bittner have used 3D printing to fabricate what they believe will eventually be a suitable material for implantation.Their results are reported in Acta Biomaterialia.”Athletes are disproportionately affected by these injuries, but they can affect everybody,” said Bittner, a third-year bioengineering graduate student at Rice, a National Science Foundation fellow and lead author of the paper. “I think this will be a powerful tool to help people with common sports injuries.”The key is mimicking tissue that turns gradually from cartilage (chondral tissue) at the surface to bone (osteo) underneath. The Biomaterials Lab at Rice printed a scaffold with custom mixtures of a polymer for the former and a ceramic for the latter with imbedded pores that would allow the patient’s own cells and blood vessels to infiltrate the implant, eventually allowing it to become part of the natural bone and cartilage.”For the most part, the composition will be the same from patient to patient,” Bittner said. “There’s porosity included so vasculature can grow in from the native bone. We don’t have to fabricate the blood vessels ourselves.”The future of the project will involve figuring out how to print an osteochondral implant that perfectly fits the patient and allows the porous implant to grow into and knit with the bone and cartilage.Mikos said the collaboration is a great early success for the Center for Engineering Complex Tissues (CECT), a National Institutes of Health center at Maryland, Rice and the Wake Forest School of Medicine developing bioprinting tools to address basic scientific questions and translate new knowledge into clinical practice.”In that context, what we’ve done here is impactful and may lead to new regenerative medicine solutions,” Mikos said. Source:http://news.rice.edu/2019/03/28/3d-printed-tissues-may-keep-athletes-in-action-2/last_img read more

Exemptions surge as parents and doctors do Hail Mary around vaccine laws

first_imgReviewed by James Ives, M.Psych. (Editor)Apr 5 2019At two public charter schools in the Sonoma wine country town of Sebastopol, more than half the kindergartners received medical exemptions from state-required vaccines last school year. The cities of Berkeley, Santa Cruz, Nevada City, Arcata and Sausalito all had schools in which more than 30% of the kindergartners had been granted such medical exemptions.Nearly three years ago, with infectious disease rates ticking up, California enacted a fiercely contested law barring parents from citing personal or religious beliefs to avoid vaccinating their children. Children could be exempted only on medical grounds, if the shots were harmful to health.Yet today, many of the schools that had the highest rates of unvaccinated students before the new measure continue to hold that alarming distinction. That’s because parents have found end runs around the new law requiring vaccinations. And they have done so, often, with the cooperation of doctors — some not even pediatricians. One prolific exemption provider is a psychiatrist who runs an anti-aging clinic.Doctors in California have broad authority to grant medical exemptions to vaccination, and to decide the grounds for doing so. Some are wielding that power liberally and sometimes for cash: signing dozens — even hundreds — of exemptions for children in far-off communities.”It’s sort of the Hail Mary of the vaccine refusers who are trying to circumvent SB 277,” the California Senate bill signed into law by Gov. Jerry Brown in 2015, said Dr. Brian Prystowsky, a Santa Rosa pediatrician. “It’s really scary stuff. We have pockets in our community that are just waiting for measles to rip through their schools.”The number of California children granted medical exemptions from vaccinations has tripled in the past two years.Across the nation, 2019 is shaping up to be one of the worst years for U.S. measles cases in a quarter-century, with major outbreaks in New York, Texas and Washington state, and new cases reported in 12 more states, including California. California’s experience underlines how hard it is to get parents to comply with vaccination laws meant to protect public safety when a small but adamant population of families and physicians seems determined to resist.When Senate Bill 277 took effect in 2016, California became the third state, after Mississippi and West Virginia, to ban vaccine exemptions based on personal or religious beliefs for public and private school students. (The ban does not apply to students who are home-schooled.)In the two subsequent years, SB 277 improved overall child vaccination rates: The percentage of fully vaccinated kindergartners rose from 92.9% in the 2015-16 school year to 95.1% in 2017-18.But those gains stalled last year due to the dramatic rise in medical exemptions: More than 4,000 kindergartners received these exemptions in the 2017-18 school year. Though the number is still relatively small, many are concentrated in a handful of schools, leaving those classrooms extremely vulnerable to serious outbreaks.Based on widely accepted federal guidelines, vaccine exemptions for medical reasons should be exceedingly rare. They’re typically reserved for children who are allergic to vaccine components, who have had a previous reaction to a vaccine, or whose immune systems are compromised, including kids being treated for cancer. Run-of-the-mill allergies and asthma aren’t reasons to delay or avoid vaccines, according to the U.S. Centers for Disease Control and Prevention. Neither is autism.Before California’s immunization law took effect, just a fraction of 1% of the state’s schoolchildren had medical exemptions. By last school year, 105 schools, scattered across the state, reported that 10% or more of their kindergartners had been granted medical exemptions. In 31 of those schools, 20% or more of the kindergartners had medical exemptions.The spike in medical exemptions is taking place amid a politically tinged, often rancorous national conversation over vaccines and personal liberty as measles resurges in the U.S. and worldwide. At least 387 cases of measles had been reported nationwide through March 28, according to the CDC. In California, 16 cases had been reported, two of them requiring hospitalization.The problem in California, state officials say, is how the immunization law was structured. It removed the ability of parents to cite “personal belief” as a reason for exempting their children from vaccine requirements in day care and schools. Exemptions now must be authorized by a licensed physician who provides a written statement citing a medical condition that indicates immunization “is not considered safe.”But the law does not specify the conditions that qualify a student for a medical exemption, nor does it require physicians to follow federal guidelines.The wording has led to a kind of gray market in which parents share names of “vaccine-friendly” doctors by word of mouth or in closed Facebook groups. And some of those doctors are granting children blanket exemptions — for all time and all vaccines — citing a range of conditions not supported by federal guidelines, such as a family history of eczema or arthritis.Amid growing concerns about suspect exemptions, the California Department of Public Health recently launched a review of schools with “biologically unlikely” numbers of medical exemptions, said the agency’s director, Dr. Karen Smith. Doctors who have written questionable exemptions will be referred to the Medical Board of California for possible investigation.The medical board, which licenses doctors, has the authority to levy sanctions if physicians have not followed standard medical practice in examining patients or documenting specific reasons for an exemption.Related StoriesNew shingles vaccine reduces outbreaks of painful rash among stem cell transplant patientsUM scientists receive $3.3 million NIH contract to develop opioid addiction vaccine$3.1 million NIH funding awarded to develop universal flu vaccineIn recent years, however, the board has sanctioned only one doctor for inappropriately writing a medical vaccine exemption in a case that made headlines. Since 2013, the board has received 106 complaints about potentially improper vaccine exemptions, including nine so far this year, said spokesman Carlos Villatoro.One pending case involves Dr. Ron Kennedy, who was trained as a psychiatrist and now runs an anti-aging clinic in Santa Rosa.Medical board investigators took the unusual step of subpoenaing 12 school districts for student medical records after receiving complaints that Kennedy was writing inappropriate  exemptions. They found that Kennedy had written at least 50 exemptions, using nearly identical form letters, for students in multiple communities, including Santa Rosa, Fremont and Fort Bragg, saying that immunizations were “contraindicated” for a catchall list of conditions including lupus, learning disability, food allergies and “detoxification impairment.”Dr. Dean Blumberg, chief of pediatric infectious diseases at UC Davis Children’s Hospital and the medical board’s expert witness, said that the exemptions issued by Kennedy appear to have been provided “without an appropriate evaluation,” according to court documents.Kennedy has refused to respond to the board’s subpoenas seeking the medical records of three of his patients, according to court documents. The board has yet to file a formal accusation against Kennedy, and he continues to practice.Like Kennedy, many of the doctors granting unorthodox exemptions cite their belief in parental rights or reference concerns not supported by conventional medical science. Kennedy is suing the medical board and its parent agency, the California Department of Consumer Affairs, saying the state did not have the legal right to subpoena school districts for his patients’ medical records without first informing him so he could challenge the action in court. The case is ongoing.Kennedy declined comment to Kaiser Health News. “I don’t want to be out in the open,” he said in a brief phone exchange. “I’ve got to go. I’ve got a business to run.”In Monterey, Dr. Douglas Hulstedt is known as the doctor to see for families seeking medical exemptions. In a brief phone interview, he said he was worried about being targeted by the state medical board. “I have stuck my neck way out there just talking with you,” he said. Hulstedt does not give exemptions to every child he examines, he said, but does believe vaccines can cause autism — a fringe viewpoint that has been debunked by multiple studies.In March, the online publication Voice of San Diego highlighted doctors who write medical exemptions, including one physician who had written more than a third of the 486 student medical exemptions in the San Diego Unified School District. District officials had compiled a list of such exemptions and the doctors who provided them.State Sen. Richard Pan (D-Sacramento), a pediatrician who sponsored California’s vaccine law, has been a vocal critic of doctors he says are skirting the intent of the legislation by handing out “fake” exemptions. Last month, he introduced follow-up legislation that would require the state health department to sign off on medical exemptions. The department also would have the authority to revoke exemptions found to be inconsistent with CDC guidelines.”We cannot allow a small number of unethical physicians to put our children back at risk,” Pan said. “It’s time to stop fake medical exemptions and the doctors who are selling them.”California Healthline digital reporter Harriet Blair Rowan and California politics correspondent Samantha Young contributed to this report.This KHN story first published on California Healthline, a service of the California Health Care Foundation. This article was reprinted from khn.org with permission from the Henry J. Kaiser Family Foundation. Kaiser Health News, an editorially independent news service, is a program of the Kaiser Family Foundation, a nonpartisan health care policy research organization unaffiliated with Kaiser Permanente.last_img read more

Poll finds youth distrust social media planning to vote

A new IOP poll finds that young adults have little faith in public institutions or big tech companies, and that they are extremely politically motivated in the lead up to this fall’s midterm elections. Credit: Elaine Thompson/AP On the heels of the March for Our Lives, the recent national gun-control protest led by young people, it’s perhaps less surprising that the poll found that young people are increasingly engaged in politics and, significantly in advance of this fall’s midterm elections, are planning to vote in greater numbers.Overall, 37 percent of those under 30 said they will “definitely be voting,” compared with 23 percent who said the same before the last midterm election in 2014, and 31 percent in 2010.”This is the most interest we’ve seen in midterm voting in the history of our poll,” which started in 1999, said John Della Volpe, the IOP’s polling director.Young Democrats are driving nearly all of the increase in enthusiasm, the poll found. A majority (51 percent) reported that they will definitely vote in November, an increase of 9 percentage points since November, and significantly more than the 36 percent of Republicans who said the same. At this juncture in the 2014 election cycle, 28 percent of Democrats and 31 percent of Republicans indicated that they would definitely be voting.Preference for Democratic control of Congress has grown since the last poll by the IOP, which conducts such surveys twice yearly. In the fall, there was a 32-point partisan gap among the most likely young voters, 65 percent preferring Democrats to control Congress, and 33 percent favoring Republicans. Now the gap has increased to 41 points, with 69 percent supporting Democrats and 28 percent Republicans.Saying that respondents expressed “an intensity unmatched in recent times,” Della Volpe predicted that this intensity is “likely to only grow hotter as the election draws near. Young people are angry, and every incumbent in America ought to understand this.”The poll “demonstrates that young people across the country are more engaged than ever,” and the findings have “enormous implications for policymakers and for those of us who care about civic engagement and student participation,” said Mark Gearan ’78, the IOP’s new director.Despite these shifts in voter support, President Trump’s approval remained the same as in the last IOP poll: 25 percent approved of his performance, while 72 percent disapproved.Trump’s highest marks came on his handling of the economy, where a third of respondents (34 percent) approved of his efforts (‒3 since fall), ISIS (31 percent now, ‒1 since fall), and tax reform (31 percent, +2 since fall). His lowest marks came on his handling of race relations (21 percent approved, ‒1 since fall) and gun violence (24 percent approved, ‒6 since fall).His approval ratings on both North Korea and health care were at 27 percent and on climate change at 22 percent. Approval of Congressional Democrats came in at 41 percent, (‒1 since fall) and of Republicans at 24 percent (+1 since fall).This poll of 2,631 18- to 29- year-olds, which was organized with undergraduate students from the Harvard Public Opinion Project, was conducted using GfK’s probability-based online sampling methodology between March 8 and March 25. The margin of error for the poll is +/‒ 2.54 percentage points at the 95 percent confidence level. Obama more trusted, young adults making the case for a second term, Harvard poll finds As debate swirls about tech companies’ responsibility to protect their users’ data and Congress questions Facebook CEO Mark Zuckerberg about third parties mining information about millions of site users, a new poll suggests that the romance between college-age Americans and social media may be cooling, or at least isn’t passionate. According to a national poll of 18- to 29-year-olds conducted by the Harvard Kennedy School’s Institute of Politics (IOP), their trust in an array of public institutions, along with some of the world’s best-known technology companies—Twitter, Uber, and Facebook—is low.When it came to politics, the poll also found that young people are planning to vote in far greater numbers in this fall’s midterm elections.Before news broke that the political consulting firm Cambridge Analytica misused the data of millions of Facebook users in the 2016 election, the Harvard Public Opinion Project dug into young Americans’ views of major technology companies.The poll found that Facebook, Twitter, and Uber are trusted much less than Amazon and Google. Only 26 percent of those surveyed said they trusted Facebook “all” or “most of the time,” while 27 percent and 28 percent said they trusted Twitter and Uber, respectively. Nearly a quarter of 18- to 29-year-olds (22 percent to 24 percent) said they “never” trust these companies.The young people’s mistrust of tech giants appeared targeted, with Amazon and Google were still held in relatively high esteem. Overall, 45 percent indicated they trusted Amazon, and 44 percent reported they trusted Google all or most of the time. Just 14 percent said they never trusted Amazon, and 15 percent said the same about Google.In sharp contrast, college and university administrators topped the list of most trusted institutions in the survey. Overall, 61 percent of college students reported trusting their administration all or most of the time, which placed colleges and universities ahead of the U.S. military (51 percent), the Department of Justice (45 percent), the Supreme Court (43 percent), and the FBI (42 percent).As in last year’s poll, the least-trusted institutions among young adults were Congress (only 17 percent trust it all or most of the time), the media (16 percent), and Wall Street (14 percent). Provided by Harvard University Explore further Citation: Poll finds youth distrust social media, planning to vote (2018, April 11) retrieved 18 July 2019 from https://phys.org/news/2018-04-poll-youth-distrust-social-media.html This story is published courtesy of the Harvard Gazette, Harvard University’s official newspaper. For additional university news, visit Harvard.edu. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. read more

Arms licences of Uttarakhand MLA Kunwar Pranav Singh Champion seen dancing with

first_imgArms licences of Uttarakhand MLA Kunwar Pranav Singh Champion seen dancing with guns suspendedUnder the notice, Uttarakhand MLA Kunwar Pranav Singh Champion has been asked to reply within 15 days as to why the licences of all the three weapons should not be cancelledadvertisement Indo-Asian News Service DehradunJuly 13, 2019UPDATED: July 13, 2019 18:26 IST Uttarakhand MLA Kunwar Pranav Singh Champion is seen holding a pistol in his mouth and a carbine in one hand while there is another pistol in the other hand.Three arms licenses of Uttarakhand MLA Kunwar Pranav Singh Champion, seen dancing with two pistols and a carbine in a viral video, have been suspended, officials said on Saturday.Suspended from the party for an indefinite period after the video came out, the BJP MLA has also got a notice from the party why he should not be expelled.”After getting reports from the Haridwar police, I have suspended three licences of (Kunwar Pranav Singh) Champion,” District Magistrate Dipendra Kumar Chaudhary said.Under the notice, Champion has been asked to reply within 15 days as to why the licences of all the three weapons should not be cancelled, he added.The action came following a report by Haridwar Senior Superintendent of Police Janmejay Khanduri that the licenses of the three weapons – a double barrel rifle, a revolver and a modified carbine, should be cancelled on security and safety reasons.”There are some cases against Champion. So we have decided to recommend the cancellation of the licences,” said Khanduri.Champion has criticized the move saying his son, who is a shooter, used to practice with these weapons. “With this decision, the sports future of my son looks bleak,” he told his supporters.State BJP President Ajay Bhatt on Wednesday had served notice seeking Champion explain why he should not be expelled as the opposition launched scathing attack on the ruling party on the issue. Led by state Congress Vice President Suryakant Dhasmana, a host of Congress leaders sought strict action against Champion – a former Congress MLA – on the basis of this video and called for filing an FIR against him.”In a section of media there are reports that Champion has been expelled from the party. But we want to clarify that a decision to expel Champion would be taken after the reply of Champion to the notice,” state BJP spokesman Devendra Bhasin said.He also said that senior party leaders have also asked the central leadership to decide on the expulsion of Champion.On the other hand, senior police officials clarified that no FIR has been filed against Champion so far in the incident. The application regarding the FIR has been forwarded to Haridwar for further action, said a police official.Dancing to the tune of “Gup Chup” song from Bollywood blockbuster “Karan Arjun”, Champion is seen holding a pistol in his mouth and a carbine in one hand while there is another pistol in the other hand. Holding a glass of whiskey, he is even seen allegedly abusing Uttarakhand.After remaining in controversies for a long time, Champion had been suspended for three months by the ruling BJP last month, after a preliminary report prepared by the state party unit’s disciplinary committee found him guilty of gross indiscipline and also took cognizance of his alleged threats to a journalist.A video had gone viral last month also in which Champion, the MLA from Khanpur, was seen threatening an electronic media journalist.He was also in the news for publicly making fun of fellow party MLA Deshraj Karnawal, and later challenging him to a wrestling match to settle their long-standing dispute. Karnwal however did not turn up for the match.Champion, who wanted a ticket for his wife for the Lok Sabha polls from Haridwar, had described the then sitting MP from the seat and now Union HRD Minister Ramesh Pokhriyal Nishank as a “migratory bird”.Champion was among the nine Congress MLAs who had rebelled against then Chief Minister Harish Rawat and crossed over to the BJP in 2016. Later all the nine MLAs were disqualified by the Speaker under the anti-defection law.ALSO READ | Viral video edited, intrusion into my privacy: BJP MLA Kunwar Pranav Singh ChampionALSO WATCH | Drunk BJP MLA Pranav Singh Champion brandishes guns while dancingFor the latest World Cup news, live scores and fixtures for World Cup 2019, log on to indiatoday.in/sports. Like us on Facebook or follow us on Twitter for World Cup news, scores and updates.Get real-time alerts and all the news on your phone with the all-new India Today app. Download from Post your comment Do You Like This Story? Awesome! Now share the story Too bad. Tell us what you didn’t like in the comments Posted bySnigdha Choudhury Nextlast_img read more

Karnataka crisis 4 MLAs leave Renaissance hotel in Mumbai

first_imgKarnataka crisis: 4 MLAs leave Renaissance hotel in MumbaiFour MLAs, including BC Patil, were spotted leaving the hotel in a car towards Siddhivinayak temple. However, their destination could not be confirmed.advertisement India Today Web Desk New DelhiJuly 12, 2019UPDATED: July 12, 2019 18:45 IST BC Patil (seen in centre in black shirt) was among four MLAs who left the hotel on Friday afternoon (ANI photo | File)Moments after Karnataka Chief Minister HD Kumaraswamy sought to move trust vote in the assembly, four out of 10 MLAs staying at the Renaissance hotel in Mumbai left the premises. BC Patil was among the MLAs who left the hotel.They were spotted leaving the hotel in a car towards Siddhivinayak temple. However, their destination could not be confirmed.Congress and JD (S) have issued a whip to their MLAs asking them to attend the ongoing budget session in the assembly or face action. However, the MLAs have said that the whip is not applicable as they have already resigned as legislators.But, Supreme Court has directed Speaker Ramesh Kumar to maintain status quo on the resignations tendered by 10 rebel MLAs, who had moved the court against him. The court asked the speaker not take any decision on resignation or disqualification until the court has had time to go through all the facts in the matter.Read | Why is Karnataka government always in jeopardy?Read | Karnataka crisis: CM Kumaraswamy seeks floor test, says he is ready for anythingRead | Karnataka crisis: No decision on rebel MLAs till July 16, SC tells SpeakerWatch | Karnataka crisis: Rebel MLAs return to MumbaiFor the latest World Cup news, live scores and fixtures for World Cup 2019, log on to indiatoday.in/sports. Like us on Facebook or follow us on Twitter for World Cup news, scores and updates.Get real-time alerts and all the news on your phone with the all-new India Today app. Download from Post your comment Do You Like This Story? Awesome! Now share the story Too bad. Tell us what you didn’t like in the comments Posted byArshi Aggarwal Nextlast_img read more